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Calcium influx, oxidative stress, and apoptosis induced by TRPV1 in chronic myeloid leukemia cells: Synergistic effects with imatinib

Introduction: Calcium flux is the master second messenger that influences the proliferation–apoptosis balance. The ability of calcium flux alterations to reduce cell growth makes ion channels interesting targets for therapy. Among all, we focused on transient receptor potential vanilloid 1, a ligand...

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Detalles Bibliográficos
Autores principales: Maggi, Federica, Morelli, Maria Beatrice, Aguzzi, Cristina, Zeppa, Laura, Nabissi, Massimo, Polidori, Carlo, Santoni, Giorgio, Amantini, Consuelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975599/
https://www.ncbi.nlm.nih.gov/pubmed/36876044
http://dx.doi.org/10.3389/fmolb.2023.1129202