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New perspective for an old drug: Can naloxone be considered an antioxidant agent?

BACKGROUND: Experimental evidence indicates that Naloxone (NLX) holds antioxidant properties. The present study aims at verifying the hypothesis that NLX could prevent oxidative stress induced by hydrogen peroxide (H(2)O(2)) in PC12 cells. METHODS: To investigate the antioxidant effect of NLX, initi...

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Detalles Bibliográficos
Autores principales: Migheli, Rossana, Lostia, Giada, Galleri, Grazia, Rocchitta, Gaia, Serra, Pier Andrea, Campesi, Ilaria, Bassareo, Valentina, Acquas, Elio, Peana, Alessandra T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975616/
https://www.ncbi.nlm.nih.gov/pubmed/36875795
http://dx.doi.org/10.1016/j.bbrep.2023.101441