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P. gingivalis Infection Upregulates PD-L1 Expression on Dendritic Cells, Suppresses CD8(+) T-cell Responses, and Aggravates Oral Cancer

Accumulating evidence shows that PD-L1 expression on dendritic cells (DC) is critical for cancer immunotherapy and that Porphyromonas gingivalis (Pg) colonization aggravates the progression of upper gastrointestinal cancers. However, the effects of Pg infection on PD-L1 expression on DCs and related...

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Detalles Bibliográficos
Autores principales: Ren, Junling, Han, Xiao, Lohner, Hannah, Hoyle, Rosalie G., Li, Jiong, Liang, Shuang, Wang, Huizhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975670/
https://www.ncbi.nlm.nih.gov/pubmed/36633576
http://dx.doi.org/10.1158/2326-6066.CIR-22-0541