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CD8(+) T cell–Dependent Remodeling of the Tumor Microenvironment Overcomes Chemoresistance

The therapeutic efficacy of chemotherapy is in part a result of its ability to enhance adaptive antitumor immune responses. However, tumor cells exploit various evasion mechanisms to escape the immune attack and blunt chemosensitivity. Herein, we report that through single-cell profiling of the tumo...

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Detalles Bibliográficos
Autores principales: Lao, Liyan, Zeng, Wenfeng, Huang, Penghan, Chen, Huiping, Jia, Zishuo, Wang, Pei, Huang, Di, Chen, Jianing, Nie, Yan, Yang, Linbin, Wu, Wei, Liu, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975671/
https://www.ncbi.nlm.nih.gov/pubmed/36603133
http://dx.doi.org/10.1158/2326-6066.CIR-22-0356