Discovery of Targets for Immune–Metabolic Antitumor Drugs Identifies Estrogen-Related Receptor Alpha

Drugs that kill tumors through multiple mechanisms have the potential for broad clinical benefits. Here, we first developed an in silico multiomics approach (BipotentR) to find cancer cell–specific regulators that simultaneously modulate tumor immunity and another oncogenic pathway and then used it...

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Detalles Bibliográficos
Autores principales: Sahu, Avinash, Wang, Xiaoman, Munson, Phillip, Klomp, Jan P.G., Wang, Xiaoqing, Gu, Shengqing Stan, Han, Ya, Qian, Gege, Nicol, Phillip, Zeng, Zexian, Wang, Chenfei, Tokheim, Collin, Zhang, Wubing, Fu, Jingxin, Wang, Jin, Nair, Nishanth Ulhas, Rens, Joost A.P., Bourajjaj, Meriem, Jansen, Bas, Leenders, Inge, Lemmers, Jaap, Musters, Mark, van Zanten, Sanne, van Zelst, Laura, Worthington, Jenny, Liu, Jun S., Juric, Dejan, Meyer, Clifford A., Oubrie, Arthur, Liu, X. Shirley, Fisher, David E., Flaherty, Keith T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975674/
https://www.ncbi.nlm.nih.gov/pubmed/36745048
http://dx.doi.org/10.1158/2159-8290.CD-22-0244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975674/
https://www.ncbi.nlm.nih.gov/pubmed/36745048
http://dx.doi.org/10.1158/2159-8290.CD-22-0244

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