MUC1-C Dictates PBRM1-Mediated Chronic Induction of Interferon Signaling, DNA Damage Resistance, and Immunosuppression in Triple-Negative Breast Cancer

The polybromo-1 (PBRM1) chromatin-targeting subunit of the SWI/SNF PBAF chromatin remodeling complex drives DNA damage resistance and immune evasion in certain cancer cells through mechanisms that remain unclear. STAT1 and IRF1 are essential effectors of type I and II IFN pathways. Here, we report t...

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Detalles Bibliográficos
Autores principales: Yamashita, Nami, Morimoto, Yoshihiro, Fushimi, Atsushi, Ahmad, Rehan, Bhattacharya, Atrayee, Daimon, Tatsuaki, Haratake, Naoki, Inoue, Yuka, Ishikawa, Satoshi, Yamamoto, Masaaki, Hata, Tsuyoshi, Akiyoshi, Sayuri, Hu, Qiang, Liu, Tao, Withers, Henry, Liu, Song, Shapiro, Geoffrey I., Yoshizumi, Tomoharu, Long, Mark D., Kufe, Donald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
New Horizons in Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975675/
https://www.ncbi.nlm.nih.gov/pubmed/36445328
http://dx.doi.org/10.1158/1541-7786.MCR-22-0772

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975675/
https://www.ncbi.nlm.nih.gov/pubmed/36445328
http://dx.doi.org/10.1158/1541-7786.MCR-22-0772

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