Cargando…
Crystallographic data of an importin-α3 dimer in which the two protomers are bridged by a bipartite nuclear localization signal
53BP1 (TP53-binding protein 1), a key player in DNA double-strand break repair, has a classical bipartite nuclear localization signal (NLS) of sequence 1666-GKRKLITSEEERSPAKRGRKS-1686 that binds to importin-α, a nuclear import adaptor protein. Nucleoporin Nup153 is involved in nuclear import of 53BP...
| Autor principal: | |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975678/ https://www.ncbi.nlm.nih.gov/pubmed/36875212 http://dx.doi.org/10.1016/j.dib.2023.108988 |