Protocol for modulation of the serotonergic DR-PBC neural circuit to prevent SUDEP in the acoustic and PTZ-induced DBA/1 mouse models of SUDEP

The dorsal raphe nucleus (DR) and the pre-Bötzinger complex (PBC) may play an important role in regulating seizure-induced respiratory arrest (S-IRA), the main contributor to sudden unexpected death in epilepsy. Here, we describe pharmacological, optogenetic, and retrograde labeling approaches to sp...

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Detalles Bibliográficos
Autores principales: Wang, YuLing, Xu, Qing, Yu, Qian, Gu, LeYuan, Ma, HaiXiang, Shen, Yue, Lian, XiTing, Shao, WeiHui, Gu, JiaXuan, Liu, Lu, Zhang, HongHai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975696/
https://www.ncbi.nlm.nih.gov/pubmed/36861823
http://dx.doi.org/10.1016/j.xpro.2023.102129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975696/
https://www.ncbi.nlm.nih.gov/pubmed/36861823
http://dx.doi.org/10.1016/j.xpro.2023.102129

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