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Protocol for modulation of the serotonergic DR-PBC neural circuit to prevent SUDEP in the acoustic and PTZ-induced DBA/1 mouse models of SUDEP
The dorsal raphe nucleus (DR) and the pre-Bötzinger complex (PBC) may play an important role in regulating seizure-induced respiratory arrest (S-IRA), the main contributor to sudden unexpected death in epilepsy. Here, we describe pharmacological, optogenetic, and retrograde labeling approaches to sp...
Autores principales: | Wang, YuLing, Xu, Qing, Yu, Qian, Gu, LeYuan, Ma, HaiXiang, Shen, Yue, Lian, XiTing, Shao, WeiHui, Gu, JiaXuan, Liu, Lu, Zhang, HongHai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975696/ https://www.ncbi.nlm.nih.gov/pubmed/36861823 http://dx.doi.org/10.1016/j.xpro.2023.102129 |
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