EWSR1 prevents the induction of aneuploidy through direct regulation of Aurora B

EWSR1 (Ewing sarcoma breakpoint region 1) was originally identified as a part of an aberrant EWSR1/FLI1 fusion gene in Ewing sarcoma, the second most common pediatric bone cancer. Due to formation of the EWSR1/FLI1 fusion gene in the tumor genome, the cell loses one wild type EWSR1 allele. Our previ...

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Detalles Bibliográficos
Autores principales: Kim, Haeyoung, Park, Hyewon, Schulz, Evan T., Azuma, Yoshiaki, Azuma, Mizuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975954/
https://www.ncbi.nlm.nih.gov/pubmed/36875767
http://dx.doi.org/10.3389/fcell.2023.987153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975954/
https://www.ncbi.nlm.nih.gov/pubmed/36875767
http://dx.doi.org/10.3389/fcell.2023.987153

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