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EWSR1 prevents the induction of aneuploidy through direct regulation of Aurora B
EWSR1 (Ewing sarcoma breakpoint region 1) was originally identified as a part of an aberrant EWSR1/FLI1 fusion gene in Ewing sarcoma, the second most common pediatric bone cancer. Due to formation of the EWSR1/FLI1 fusion gene in the tumor genome, the cell loses one wild type EWSR1 allele. Our previ...
Autores principales: | Kim, Haeyoung, Park, Hyewon, Schulz, Evan T., Azuma, Yoshiaki, Azuma, Mizuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975954/ https://www.ncbi.nlm.nih.gov/pubmed/36875767 http://dx.doi.org/10.3389/fcell.2023.987153 |
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