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L-kynurenine induces NK cell loss in gastric cancer microenvironment via promoting ferroptosis

BACKGROUND: Natural killer (NK) cells play a major role in body’s fighting against various types of cancers. Their infiltration in the tumor microenvironment (TME) of gastric cancer (GC) are significantly decreased, which has been reported as a robust prognostic marker. However, the causes leading t...

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Detalles Bibliográficos
Autores principales: Cui, Jian-Xin, Xu, Xian-Hui, He, Tao, Liu, Jia-Jia, Xie, Tian-Yu, Tian, Wen, Liu, Jun-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976385/
https://www.ncbi.nlm.nih.gov/pubmed/36855135
http://dx.doi.org/10.1186/s13046-023-02629-w