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Monocyte-derived cells invade brain parenchyma and amyloid plaques in human Alzheimer’s disease hippocampus

Microglia are brain-resident myeloid cells and play a major role in the innate immune responses of the CNS and the pathogenesis of Alzheimer's disease (AD). However, the contribution of nonparenchymal or brain-infiltrated myeloid cells to disease progression remains to be demonstrated. Here, we...

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Detalles Bibliográficos
Autores principales: Muñoz-Castro, Clara, Mejias-Ortega, Marina, Sanchez-Mejias, Elisabeth, Navarro, Victoria, Trujillo-Estrada, Laura, Jimenez, Sebastian, Garcia-Leon, Juan Antonio, Fernandez-Valenzuela, Juan Jose, Sanchez-Mico, Maria Virtudes, Romero-Molina, Carmen, Moreno-Gonzalez, Ines, Baglietto-Vargas, David, Vizuete, Marisa, Gutierrez, Antonia, Vitorica, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976401/
https://www.ncbi.nlm.nih.gov/pubmed/36855152
http://dx.doi.org/10.1186/s40478-023-01530-z