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Small molecule drugs promote repopulation of transplanted hepatocytes by stimulating cell dedifferentiation
BACKGROUND & AIMS: Hepatocyte transplantation has emerged as a possible treatment option for end-stage liver disease. However, an important obstacle to therapeutic success is the low level of engraftment and proliferation of transplanted hepatocytes, which do not survive long enough to exert the...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976449/ https://www.ncbi.nlm.nih.gov/pubmed/36873420 http://dx.doi.org/10.1016/j.jhepr.2023.100670 |