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Small molecule drugs promote repopulation of transplanted hepatocytes by stimulating cell dedifferentiation
BACKGROUND & AIMS: Hepatocyte transplantation has emerged as a possible treatment option for end-stage liver disease. However, an important obstacle to therapeutic success is the low level of engraftment and proliferation of transplanted hepatocytes, which do not survive long enough to exert the...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976449/ https://www.ncbi.nlm.nih.gov/pubmed/36873420 http://dx.doi.org/10.1016/j.jhepr.2023.100670 |