Virtual screening, pharmacokinetic, and DFT studies of anticancer compounds as potential V600E-BRAF kinaseinhibitors

OBJECTIVES: V600E-BRAF kinase is an essential therapeutic target in melanoma and other types of tumors. Because of its resistance to known inhibitors and the adverse effects of some identified inhibitors, investigation of new potent inhibitors is necessary. METHODS: In the present work, in silico st...

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Detalles Bibliográficos
Autores principales: Umar, Abdullahi B., Uzairu, Adamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taibah University 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976450/
https://www.ncbi.nlm.nih.gov/pubmed/36875340
http://dx.doi.org/10.1016/j.jtumed.2023.01.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976450/
https://www.ncbi.nlm.nih.gov/pubmed/36875340
http://dx.doi.org/10.1016/j.jtumed.2023.01.013

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