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Multiple potassium channel tetramerization domain (KCTD) family members interact with Gβγ, with effects on cAMP signaling
G protein–coupled receptors (GPCRs) initiate an array of intracellular signaling programs by activating heterotrimeric G proteins (Gα and Gβγ subunits). Therefore, G protein modifiers are well positioned to shape GPCR pharmacology. A few members of the potassium channel tetramerization domain (KCTD)...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976452/ https://www.ncbi.nlm.nih.gov/pubmed/36736897 http://dx.doi.org/10.1016/j.jbc.2023.102924 |