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Multiple potassium channel tetramerization domain (KCTD) family members interact with Gβγ, with effects on cAMP signaling

G protein–coupled receptors (GPCRs) initiate an array of intracellular signaling programs by activating heterotrimeric G proteins (Gα and Gβγ subunits). Therefore, G protein modifiers are well positioned to shape GPCR pharmacology. A few members of the potassium channel tetramerization domain (KCTD)...

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Detalles Bibliográficos
Autores principales: Sloan, Douglas C., Cryan, Casey E., Muntean, Brian S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976452/
https://www.ncbi.nlm.nih.gov/pubmed/36736897
http://dx.doi.org/10.1016/j.jbc.2023.102924