PRC2-independent actions of H3.3K27M in embryonic stem cell differentiation

The histone H3 variant, H3.3, is localized at specific regions in the genome, especially promoters and active enhancers, and has been shown to play important roles in development. A lysine to methionine substitution in position 27 (H3.3K27M) is a main cause of Diffuse Intrinsic Pontine Glioma (speci...

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Detalles Bibliográficos
Autores principales: Cohen, Lea R Z, Kaffe, Binyamin, Deri, Eden, Leibson, Chen, Nissim-Rafinia, Malka, Maman, Moria, Harpaz, Nofar, Ron, Guy, Shema, Efrat, Meshorer, Eran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976889/
https://www.ncbi.nlm.nih.gov/pubmed/36156096
http://dx.doi.org/10.1093/nar/gkac800

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976889/
https://www.ncbi.nlm.nih.gov/pubmed/36156096
http://dx.doi.org/10.1093/nar/gkac800

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