Cargando…

PRC2-independent actions of H3.3K27M in embryonic stem cell differentiation

The histone H3 variant, H3.3, is localized at specific regions in the genome, especially promoters and active enhancers, and has been shown to play important roles in development. A lysine to methionine substitution in position 27 (H3.3K27M) is a main cause of Diffuse Intrinsic Pontine Glioma (speci...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cohen, Lea R Z, Kaffe, Binyamin, Deri, Eden, Leibson, Chen, Nissim-Rafinia, Malka, Maman, Moria, Harpaz, Nofar, Ron, Guy, Shema, Efrat, Meshorer, Eran
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976889/ https://www.ncbi.nlm.nih.gov/pubmed/36156096 http://dx.doi.org/10.1093/nar/gkac800

Ejemplares similares

A hyperdynamic H3.3 nucleosome marks promoter regions in pluripotent embryonic stem cells
por: Schlesinger, Sharon, et al.
Publicado: (2017)

Interdependence of PRC1 and PRC2 for recruitment to Polycomb Response Elements
por: Kahn, Tatyana G., et al.
Publicado: (2016)

The transcriptional elongation factor CTR9 demarcates PRC2-mediated H3K27me3 domains by altering PRC2 subtype equilibrium
por: Chan, Ngai Ting, et al.
Publicado: (2022)

Cooperative DNA looping by PRC2 complexes
por: Lin, Xingcheng, et al.
Publicado: (2021)

Requirement for PRC1 subunit BMI1 in host gene activation by Epstein–Barr virus protein EBNA3C
por: Paschos, Kostas, et al.
Publicado: (2019)

Bimodal regulation of the PRC2 complex by USP7 underlies tumorigenesis
por: Su, Dongxue, et al.
Publicado: (2021)

HSCARG, a novel regulator of H2A ubiquitination by downregulating PRC1 ubiquitin E3 ligase activity, is essential for cell proliferation
por: Hu, Bin, et al.
Publicado: (2014)

Three classes of response elements for human PRC2 and MLL1/2–Trithorax complexes
por: Du, Junqing, et al.
Publicado: (2018)

Bromodomain protein 7 interacts with PRMT5 and PRC2, and is involved in transcriptional repression of their target genes
por: Tae, Sookil, et al.
Publicado: (2011)

TET1 is controlled by pluripotency-associated factors in ESCs and downmodulated by PRC2 in differentiated cells and tissues
por: Neri, Francesco, et al.
Publicado: (2015)

PRMT5-mediated histone arginine methylation antagonizes transcriptional repression by polycomb complex PRC2
por: Liu, Fan, et al.
Publicado: (2020)

The long noncoding RNA Gm15055 represses Hoxa gene expression by recruiting PRC2 to the gene cluster
por: Liu, Guo-You, et al.
Publicado: (2016)

The transcriptional repressors VAL1 and VAL2 recruit PRC2 for genome-wide Polycomb silencing in Arabidopsis
por: Yuan, Liangbing, et al.
Publicado: (2020)

The testis-specific double bromodomain-containing protein BRDT forms a complex with multiple spliceosome components and is required for mRNA splicing and 3′-UTR truncation in round spermatids
por: Berkovits, Binyamin D., et al.
Publicado: (2012)

HDAC1 and PRC2 mediate combinatorial control in SPI1/PU.1-dependent gene repression in murine erythroleukaemia
por: Gregoricchio, Sebastian, et al.
Publicado: (2022)

DAXX co-folds with H3.3/H4 using high local stability conferred by the H3.3 variant recognition residues
por: DeNizio, Jamie E., et al.
Publicado: (2014)

PRC2 regulates RNA polymerase III transcribed non-translated RNA gene transcription through EZH2 and SUZ12 interaction with TFIIIC complex
por: Liu, Chang, et al.
Publicado: (2015)

Histone variant H3.3 provides the heterochromatic H3 lysine 9 tri-methylation mark at telomeres
por: Udugama, Maheshi, et al.
Publicado: (2015)

Histone H3.3 phosphorylation promotes heterochromatin formation by inhibiting H3K9/K36 histone demethylase
por: Udugama, Maheshi, et al.
Publicado: (2022)

Histone variant H3.3 stimulates HSP70 transcription through cooperation with HP1γ
por: Kim, Hyunjung, et al.
Publicado: (2011)

Dissecting the roles of the histone chaperones reveals the evolutionary conserved mechanism of transcription-coupled deposition of H3.3
por: Song, Yunkyoung, et al.
Publicado: (2013)

H3.3K4M destabilizes enhancer H3K4 methyltransferases MLL3/MLL4 and impairs adipose tissue development
por: Jang, Younghoon, et al.
Publicado: (2019)

PP1α, PP1β and Wip-1 regulate H4S47 phosphorylation and deposition of histone H3 variant H3.3
por: Zhang, Hui, et al.
Publicado: (2013)

Histone chaperone HIRA deposits histone H3.3 onto foreign viral DNA and contributes to anti-viral intrinsic immunity
por: Rai, Taranjit Singh, et al.
Publicado: (2017)

H3.Y discriminates between HIRA and DAXX chaperone complexes and reveals unexpected insights into human DAXX-H3.3-H4 binding and deposition requirements
por: Zink, Lisa-Maria, et al.
Publicado: (2017)

Dual role of histone variant H3.3B in spermatogenesis: positive regulation of piRNA transcription and implication in X-chromosome inactivation
por: Fontaine, Emeline, et al.
Publicado: (2022)

CHK1-driven histone H3.3 serine 31 phosphorylation is important for chromatin maintenance and cell survival in human ALT cancer cells
por: Chang, Fiona T. M., et al.
Publicado: (2015)

Long non-coding RNA ChRO1 facilitates ATRX/DAXX-dependent H3.3 deposition for transcription-associated heterochromatin reorganization
por: Park, Jinyoung, et al.
Publicado: (2018)

HIRA-mediated loading of histone variant H3.3 controls androgen-induced transcription by regulation of AR/BRD4 complex assembly at enhancers
por: Morozov, Viacheslav M, et al.
Publicado: (2023)

HIRA complex presets transcriptional potential through coordinating depositions of the histone variants H3.3 and H2A.Z on the poised genes in mESCs
por: Yang, Yang, et al.
Publicado: (2021)

RAG1 targeting in the genome is dominated by chromatin interactions mediated by the non-core regions of RAG1 and RAG2
por: Maman, Yaakov, et al.
Publicado: (2016)

INHAT subunit SET/TAF-Iβ regulates PRC1-independent H2AK119 mono-ubiquitination via E3 ligase MIB1 in colon cancer
por: Park, Junyoung, et al.
Publicado: (2023)

Modulation of Dnmt3b function in vitro by interactions with Dnmt3L, Dnmt3a and Dnmt3b splice variants
por: Van Emburgh, Beth O., et al.
Publicado: (2011)

Chromatin methylation activity of Dnmt3a and Dnmt3a/3L is guided by interaction of the ADD domain with the histone H3 tail
por: Zhang, Yingying, et al.
Publicado: (2010)

Rpd3L HDAC links H3K4me3 to transcriptional repression memory
por: Lee, Bo Bae, et al.
Publicado: (2018)

NuA3 HAT antagonizes the Rpd3S and Rpd3L HDACs to optimize mRNA and lncRNA expression dynamics
por: Kim, Ji Hyun, et al.
Publicado: (2020)

FUBP3 interacts with FGF9 3′ microsatellite and positively regulates FGF9 translation
por: Gau, Bing-Huang, et al.
Publicado: (2011)

The ATP-dependent chromatin remodeler Chd1 is recruited by transcription elongation factors and maintains H3K4me3/H3K36me3 domains at actively transcribed and spliced genes
por: Lee, Yaelim, et al.
Publicado: (2017)

An interaction between eIF4A3 and eIF3g drives the internal initiation of translation
por: Chang, Jeeyoon, et al.
Publicado: (2023)

Formation of nucleoprotein filaments by mammalian DNA methyltransferase Dnmt3a in complex with regulator Dnmt3L
por: Jurkowska, Renata Z., et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_j35naqdd7jtkvtpd2u5f1bpmra