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High-throughput quantitative binding analysis of DNA aptamers using exonucleases

Aptamers are nucleic acid bioreceptors that have been used in various applications including medical diagnostics and as therapeutic agents. Identifying the most optimal aptamer for a particular application is very challenging. Here, we for the first time have developed a high-throughput method for a...

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Detalles Bibliográficos
Autores principales: Canoura, Juan, Alkhamis, Obtin, Liu, Yingzhu, Willis, Connor, Xiao, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976898/
https://www.ncbi.nlm.nih.gov/pubmed/36583362
http://dx.doi.org/10.1093/nar/gkac1210