Structure of a 28.5 kDa duplex-embedded G-quadruplex system resolved to 7.4 Å resolution with cryo-EM

Genomic regions with high guanine content can fold into non-B form DNA four-stranded structures known as G-quadruplexes (G4s). Extensive in vivo investigations have revealed that promoter G4s are transcriptional regulators. Little structural information exists for these G4s embedded within duplexes,...

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Detalles Bibliográficos
Autores principales: Monsen, Robert C, Chua, Eugene Y D, Hopkins, Jesse B, Chaires, Jonathan B, Trent, John O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976903/
https://www.ncbi.nlm.nih.gov/pubmed/36715343
http://dx.doi.org/10.1093/nar/gkad014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976903/
https://www.ncbi.nlm.nih.gov/pubmed/36715343
http://dx.doi.org/10.1093/nar/gkad014

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