Transmicron: accurate prediction of insertion probabilities improves detection of cancer driver genes from transposon mutagenesis screens

Transposon screens are powerful in vivo assays used to identify loci driving carcinogenesis. These loci are identified as Common Insertion Sites (CISs), i.e. regions with more transposon insertions than expected by chance. However, the identification of CISs is affected by biases in the insertion be...

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Detalles Bibliográficos
Autores principales: Bredthauer, Carl, Fischer, Anja, Ahari, Ata Jadid, Cao, Xueqi, Weber, Julia, Rad, Lena, Rad, Roland, Wachutka, Leonhard, Gagneur, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976929/
https://www.ncbi.nlm.nih.gov/pubmed/36617985
http://dx.doi.org/10.1093/nar/gkac1215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976929/
https://www.ncbi.nlm.nih.gov/pubmed/36617985
http://dx.doi.org/10.1093/nar/gkac1215

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