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Transmicron: accurate prediction of insertion probabilities improves detection of cancer driver genes from transposon mutagenesis screens
Transposon screens are powerful in vivo assays used to identify loci driving carcinogenesis. These loci are identified as Common Insertion Sites (CISs), i.e. regions with more transposon insertions than expected by chance. However, the identification of CISs is affected by biases in the insertion be...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976929/ https://www.ncbi.nlm.nih.gov/pubmed/36617985 http://dx.doi.org/10.1093/nar/gkac1215 |