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Benchmarking of microbiome detection tools on RNA-seq synthetic databases according to diverse conditions

MOTIVATION: Here, we performed a benchmarking analysis of five tools for microbe sequence detection using transcriptomics data (Kraken2, MetaPhlAn2, PathSeq, DRAC and Pandora). We built a synthetic database mimicking real-world structure with tuned conditions accounting for microbe species prevalenc...

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Detalles Bibliográficos
Autores principales: Jurado-Rueda, Francisco, Alonso-Guirado, Lola, Perea-Cham-blee, Tomin E, Elliott, Oliver T, Filip, Ioan, Rabadán, Raúl, Malats, Núria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976984/
https://www.ncbi.nlm.nih.gov/pubmed/36874954
http://dx.doi.org/10.1093/bioadv/vbad014