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Benchmarking of microbiome detection tools on RNA-seq synthetic databases according to diverse conditions
MOTIVATION: Here, we performed a benchmarking analysis of five tools for microbe sequence detection using transcriptomics data (Kraken2, MetaPhlAn2, PathSeq, DRAC and Pandora). We built a synthetic database mimicking real-world structure with tuned conditions accounting for microbe species prevalenc...
Autores principales: | Jurado-Rueda, Francisco, Alonso-Guirado, Lola, Perea-Cham-blee, Tomin E, Elliott, Oliver T, Filip, Ioan, Rabadán, Raúl, Malats, Núria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976984/ https://www.ncbi.nlm.nih.gov/pubmed/36874954 http://dx.doi.org/10.1093/bioadv/vbad014 |
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