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Therapeutic implications of transcriptomics in head and neck cancer patient-derived xenografts

There are currently no clinical strategies utilizing tumor gene expression to inform therapeutic selection for patients with head and neck squamous cell carcinoma (HNSCC). One of the challenges in developing predictive biomarkers is the limited characterization of preclinical HNSCC models. Patient-d...

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Detalles Bibliográficos
Autores principales: Lee, Rex H., Roy, Ritu, Li, Hua, Hechmer, Aaron, Zhu, Tian Ran, Izgutdina, Adila, Olshen, Adam B., Johnson, Daniel E., Grandis, Jennifer R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977000/
https://www.ncbi.nlm.nih.gov/pubmed/36857322
http://dx.doi.org/10.1371/journal.pone.0282177