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A somatic hypermutation–based machine learning model stratifies individuals with Crohn's disease and controls

Crohn's disease (CD) is a chronic relapsing–remitting inflammatory disorder of the gastrointestinal tract that is characterized by altered innate and adaptive immune function. Although massively parallel sequencing studies of the T cell receptor repertoire identified oligoclonal expansion of un...

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Detalles Bibliográficos
Autores principales: Safra, Modi, Werner, Lael, Peres, Ayelet, Polak, Pazit, Salamon, Naomi, Schvimer, Michael, Weiss, Batia, Barshack, Iris, Shouval, Dror S., Yaari, Gur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977146/
https://www.ncbi.nlm.nih.gov/pubmed/36526432
http://dx.doi.org/10.1101/gr.276683.122