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A somatic hypermutation–based machine learning model stratifies individuals with Crohn's disease and controls
Crohn's disease (CD) is a chronic relapsing–remitting inflammatory disorder of the gastrointestinal tract that is characterized by altered innate and adaptive immune function. Although massively parallel sequencing studies of the T cell receptor repertoire identified oligoclonal expansion of un...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977146/ https://www.ncbi.nlm.nih.gov/pubmed/36526432 http://dx.doi.org/10.1101/gr.276683.122 |