Multi-omics analyses demonstrate a critical role for EHMT1 methyltransferase in transcriptional repression during oogenesis

EHMT1 (also known as GLP) is a multifunctional protein, best known for its role as an H3K9me1 and H3K9me2 methyltransferase through its reportedly obligatory dimerization with EHMT2 (also known as G9A). Here, we investigated the role of EHMT1 in the oocyte in comparison to EHMT2 using oocyte-specifi...

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Detalles Bibliográficos
Autores principales: Demond, Hannah, Hanna, Courtney W., Castillo-Fernandez, Juan, Santos, Fátima, Papachristou, Evangelia K., Segonds-Pichon, Anne, Kishore, Kamal, Andrews, Simon, D'Santos, Clive S., Kelsey, Gavin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977154/
https://www.ncbi.nlm.nih.gov/pubmed/36690445
http://dx.doi.org/10.1101/gr.277046.122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977154/
https://www.ncbi.nlm.nih.gov/pubmed/36690445
http://dx.doi.org/10.1101/gr.277046.122

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