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Multi-omics analyses demonstrate a critical role for EHMT1 methyltransferase in transcriptional repression during oogenesis
EHMT1 (also known as GLP) is a multifunctional protein, best known for its role as an H3K9me1 and H3K9me2 methyltransferase through its reportedly obligatory dimerization with EHMT2 (also known as G9A). Here, we investigated the role of EHMT1 in the oocyte in comparison to EHMT2 using oocyte-specifi...
Autores principales: | Demond, Hannah, Hanna, Courtney W., Castillo-Fernandez, Juan, Santos, Fátima, Papachristou, Evangelia K., Segonds-Pichon, Anne, Kishore, Kamal, Andrews, Simon, D'Santos, Clive S., Kelsey, Gavin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977154/ https://www.ncbi.nlm.nih.gov/pubmed/36690445 http://dx.doi.org/10.1101/gr.277046.122 |
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