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Basophil Depletion Alters Host Immunity, Intestinal Permeability, and Mammalian Host-to-Mosquito Transmission in Malaria

Malaria-induced bacteremia has been shown to result from intestinal mast cell (MC) activation. The appearance of MCs in the ileum and increased intestinal permeability to enteric bacteria are preceded by an early Th2-biased host immune response to infection, characterized by the appearance of IL-4,...

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Detalles Bibliográficos
Autores principales: Donnelly, Erinn L., Céspedes, Nora, Hansten, Gretchen, Wagers, Delaney, Briggs, Anna M., Lowder, Casey, Schauer, Joseph, Garrison, Sarah M., Haapanen, Lori, Van de Water, Judy, Luckhart, Shirley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977168/
https://www.ncbi.nlm.nih.gov/pubmed/35970557
http://dx.doi.org/10.4049/immunohorizons.2200055