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ATG16L1 adopts a dual–binding site mode to interact with WIPI2b in autophagy

Macroautophagy plays crucial roles in the regulation of cellular physiology and requires de novo synthesis of double-membrane autophagosomes, which relies on a specific interaction between autophagy-related 16L1 (ATG16L1) and WD repeat domain phosphoinositide-interacting protein 2b (WIPI2b). However...

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Detalles Bibliográficos
Autores principales: Gong, Xinyu, Wang, Yingli, Tang, Yubin, Wang, Yaru, Zhang, Mingfang, Li, Miao, Zhang, Yuchao, Pan, Lifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977175/
https://www.ncbi.nlm.nih.gov/pubmed/36857448
http://dx.doi.org/10.1126/sciadv.adf0824