Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells

Cellular metabolism is important for adult neural stem/progenitor cell (NSPC) behavior. However, its role in the transition from quiescence to proliferation is not fully understood. We here show that the mitochondrial pyruvate carrier (MPC) plays a crucial and unexpected part in this process. MPC tr...

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Detalles Bibliográficos
Autores principales: Petrelli, Francesco, Scandella, Valentina, Montessuit, Sylvie, Zamboni, Nicola, Martinou, Jean-Claude, Knobloch, Marlen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977184/
https://www.ncbi.nlm.nih.gov/pubmed/36857455
http://dx.doi.org/10.1126/sciadv.add5220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977184/
https://www.ncbi.nlm.nih.gov/pubmed/36857455
http://dx.doi.org/10.1126/sciadv.add5220

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