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Colonic Epithelial Circadian Disruption Worsens Dextran Sulfate Sodium–Induced Colitis

BACKGROUND: Disruption of central circadian rhythms likely mediated by changes in microbiota and a decrease in gut-derived metabolites like short chain fatty acids (SCFAs) negatively impacts colonic barrier homeostasis. We aimed to explore the effects of isolated peripheral colonic circadian disrupt...

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Detalles Bibliográficos
Autores principales: Jochum, Sarah B, Engen, Phillip A, Shaikh, Maliha, Naqib, Ankur, Wilber, Sherry, Raeisi, Shohreh, Zhang, Lijuan, Song, Shiwen, Sanzo, Gabriella, Chouhan, Vijit, Ko, Frank, Post, Zoe, Tran, Laura, Ramirez, Vivian, Green, Stefan J, Khazaie, Khashayarsha, Hayden, Dana M, Brown, Mark J, Voigt, Robin M, Forsyth, Christopher B, Keshavarzian, Ali, Swanson, Garth R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977234/
https://www.ncbi.nlm.nih.gov/pubmed/36287037
http://dx.doi.org/10.1093/ibd/izac219