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Colonic Epithelial Circadian Disruption Worsens Dextran Sulfate Sodium–Induced Colitis
BACKGROUND: Disruption of central circadian rhythms likely mediated by changes in microbiota and a decrease in gut-derived metabolites like short chain fatty acids (SCFAs) negatively impacts colonic barrier homeostasis. We aimed to explore the effects of isolated peripheral colonic circadian disrupt...
Autores principales: | Jochum, Sarah B, Engen, Phillip A, Shaikh, Maliha, Naqib, Ankur, Wilber, Sherry, Raeisi, Shohreh, Zhang, Lijuan, Song, Shiwen, Sanzo, Gabriella, Chouhan, Vijit, Ko, Frank, Post, Zoe, Tran, Laura, Ramirez, Vivian, Green, Stefan J, Khazaie, Khashayarsha, Hayden, Dana M, Brown, Mark J, Voigt, Robin M, Forsyth, Christopher B, Keshavarzian, Ali, Swanson, Garth R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977234/ https://www.ncbi.nlm.nih.gov/pubmed/36287037 http://dx.doi.org/10.1093/ibd/izac219 |
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