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Specific targeting of inflammatory osteoclastogenesis by the probiotic yeast S. boulardii CNCM I-745 reduces bone loss in osteoporosis

Bone destruction is a hallmark of chronic inflammation, and bone-resorbing osteoclasts arising under such a condition differ from steady-state ones. However, osteoclast diversity remains poorly explored. Here, we combined transcriptomic profiling, differentiation assays and in vivo analysis in mouse...

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Detalles Bibliográficos
Autores principales: Madel, Maria-Bernadette, Halper, Julia, Ibáñez, Lidia, Claire, Lozano, Rouleau, Matthieu, Boutin, Antoine, Mahler, Adrien, Pontier-Bres, Rodolphe, Ciucci, Thomas, Topi, Majlinda, Hue, Christophe, Amiaud, Jerome, Iborra, Salvador, Sancho, David, Heymann, Dominique, Garchon, Henri-Jean, Czerucka, Dorota, Apparailly, Florence, Duroux-Richard, Isabelle, Wakkach, Abdelilah, Blin-Wakkach, Claudine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977286/
https://www.ncbi.nlm.nih.gov/pubmed/36848406
http://dx.doi.org/10.7554/eLife.82037