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Specific targeting of inflammatory osteoclastogenesis by the probiotic yeast S. boulardii CNCM I-745 reduces bone loss in osteoporosis
Bone destruction is a hallmark of chronic inflammation, and bone-resorbing osteoclasts arising under such a condition differ from steady-state ones. However, osteoclast diversity remains poorly explored. Here, we combined transcriptomic profiling, differentiation assays and in vivo analysis in mouse...
Autores principales: | Madel, Maria-Bernadette, Halper, Julia, Ibáñez, Lidia, Claire, Lozano, Rouleau, Matthieu, Boutin, Antoine, Mahler, Adrien, Pontier-Bres, Rodolphe, Ciucci, Thomas, Topi, Majlinda, Hue, Christophe, Amiaud, Jerome, Iborra, Salvador, Sancho, David, Heymann, Dominique, Garchon, Henri-Jean, Czerucka, Dorota, Apparailly, Florence, Duroux-Richard, Isabelle, Wakkach, Abdelilah, Blin-Wakkach, Claudine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977286/ https://www.ncbi.nlm.nih.gov/pubmed/36848406 http://dx.doi.org/10.7554/eLife.82037 |
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