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Krt14 and Krt15 differentially regulate regenerative properties and differentiation potential of airway basal cells

Keratin expression dynamically changes in airway basal cells (BCs) after acute and chronic injury, yet the functional consequences of these changes on BC behavior remain unknown. In bronchiolitis obliterans (BO) after lung transplantation, BC clonogenicity declines, which is associated with a switch...

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Detalles Bibliográficos
Autores principales: Ievlev, Vitaly, Lynch, Thomas J., Freischlag, Kyle W., Gries, Caitlyn B., Shah, Anit, Pai, Albert C., Ahlers, Bethany A., Park, Soo, Engelhardt, John F., Parekh, Kalpaj R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977304/
https://www.ncbi.nlm.nih.gov/pubmed/36512409
http://dx.doi.org/10.1172/jci.insight.162041