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Interfering with lipid metabolism through targeting CES1 sensitizes hepatocellular carcinoma for chemotherapy

Hepatocellular carcinoma (HCC) is the most common lethal form of liver cancer. Apart from surgical removal and transplantation, other treatments have not yet been well established for patients with HCC. In this study, we found that carboxylesterase 1 (CES1) is expressed at various levels in HCC. We...

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Detalles Bibliográficos
Autores principales: Li, Gang, Li, Xin, Mahmud, Iqbal, Ysaguirre, Jazmin, Fekry, Baharan, Wang, Shuyue, Wei, Bo, Eckel-Mahan, Kristin L., Lorenzi, Philip L., Lehner, Richard, Sun, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977307/
https://www.ncbi.nlm.nih.gov/pubmed/36472914
http://dx.doi.org/10.1172/jci.insight.163624