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Interfering with lipid metabolism through targeting CES1 sensitizes hepatocellular carcinoma for chemotherapy
Hepatocellular carcinoma (HCC) is the most common lethal form of liver cancer. Apart from surgical removal and transplantation, other treatments have not yet been well established for patients with HCC. In this study, we found that carboxylesterase 1 (CES1) is expressed at various levels in HCC. We...
Autores principales: | Li, Gang, Li, Xin, Mahmud, Iqbal, Ysaguirre, Jazmin, Fekry, Baharan, Wang, Shuyue, Wei, Bo, Eckel-Mahan, Kristin L., Lorenzi, Philip L., Lehner, Richard, Sun, Kai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977307/ https://www.ncbi.nlm.nih.gov/pubmed/36472914 http://dx.doi.org/10.1172/jci.insight.163624 |
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