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LRP1 protects against excessive superior mesenteric artery remodeling by modulating angiotensin II–mediated signaling

Vascular smooth muscle cells (vSMCs) exert a critical role in sensing and maintaining vascular integrity. These cells abundantly express the low-density lipoprotein receptor–related protein 1 (LRP1), a large endocytic signaling receptor that recognizes numerous ligands, including apolipoprotein E–ri...

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Detalles Bibliográficos
Autores principales: Zhang, Jackie M., Au, Dianaly T., Sawada, Hisashi, Franklin, Michael K., Moorleghen, Jessica J., Howatt, Deborah A., Wang, Pengjun, Aicher, Brittany O., Hampton, Brian, Migliorini, Mary, Ni, Fenge, Mullick, Adam E., Wani, Mashhood M., Ucuzian, Areck A., Lu, Hong S., Muratoglu, Selen C., Daugherty, Alan, Strickland, Dudley K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977308/
https://www.ncbi.nlm.nih.gov/pubmed/36472907
http://dx.doi.org/10.1172/jci.insight.164751