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LRP1 protects against excessive superior mesenteric artery remodeling by modulating angiotensin II–mediated signaling
Vascular smooth muscle cells (vSMCs) exert a critical role in sensing and maintaining vascular integrity. These cells abundantly express the low-density lipoprotein receptor–related protein 1 (LRP1), a large endocytic signaling receptor that recognizes numerous ligands, including apolipoprotein E–ri...
Autores principales: | Zhang, Jackie M., Au, Dianaly T., Sawada, Hisashi, Franklin, Michael K., Moorleghen, Jessica J., Howatt, Deborah A., Wang, Pengjun, Aicher, Brittany O., Hampton, Brian, Migliorini, Mary, Ni, Fenge, Mullick, Adam E., Wani, Mashhood M., Ucuzian, Areck A., Lu, Hong S., Muratoglu, Selen C., Daugherty, Alan, Strickland, Dudley K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977308/ https://www.ncbi.nlm.nih.gov/pubmed/36472907 http://dx.doi.org/10.1172/jci.insight.164751 |
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