MRAP2 regulates energy homeostasis by promoting primary cilia localization of MC4R

The G protein–coupled receptor melanocortin-4 receptor (MC4R) and its associated protein melanocortin receptor–associated protein 2 (MRAP2) are essential for the regulation of food intake and body weight in humans. MC4R localizes and functions at the neuronal primary cilium, a microtubule-based orga...

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Detalles Bibliográficos
Autores principales: Bernard, Adelaide, Ojeda Naharros, Irene, Yue, Xinyu, Mifsud, Francois, Blake, Abbey, Bourgain-Guglielmetti, Florence, Ciprin, Jordi, Zhang, Sumei, McDaid, Erin, Kim, Kellan, Nachury, Maxence V., Reiter, Jeremy F., Vaisse, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977312/
https://www.ncbi.nlm.nih.gov/pubmed/36692018
http://dx.doi.org/10.1172/jci.insight.155900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977312/
https://www.ncbi.nlm.nih.gov/pubmed/36692018
http://dx.doi.org/10.1172/jci.insight.155900

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