TRPM7 kinase is required for insulin production and compensatory islet responses during obesity

Most overweight individuals do not develop diabetes due to compensatory islet responses to restore glucose homeostasis. Therefore, regulatory pathways that promote β cell compensation are potential targets for treatment of diabetes. The transient receptor potential cation channel subfamily M member...

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Detalles Bibliográficos
Autores principales: Khajavi, Noushafarin, Beck, Andreas, Riçku, Klea, Beyerle, Philipp, Jacob, Katharina, Syamsul, Sabrina F., Belkacemi, Anouar, Reinach, Peter S., Schreier, Pascale C.F., Salah, Houssein, Popp, Tanja, Novikoff, Aaron, Breit, Andreas, Chubanov, Vladimir, Müller, Timo D., Zierler, Susanna, Gudermann, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977431/
https://www.ncbi.nlm.nih.gov/pubmed/36574297
http://dx.doi.org/10.1172/jci.insight.163397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977431/
https://www.ncbi.nlm.nih.gov/pubmed/36574297
http://dx.doi.org/10.1172/jci.insight.163397

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