Targeting HuR-Vav3 mRNA interaction prevents Pseudomonas aeruginosa adhesion to the cystic fibrosis airway epithelium

Cystic fibrosis (CF) is characterized by chronic bacterial infections leading to progressive bronchiectasis and respiratory failure. Pseudomonas aeruginosa (Pa) is the predominant opportunistic pathogen infecting the CF airways. The guanine nucleotide exchange factor Vav3 plays a critical role in Pa...

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Detalles Bibliográficos
Autores principales: Badaoui, Mehdi, Sobolewski, Cyril, Luscher, Alexandre, Bacchetta, Marc, Köhler, Thilo, van Delden, Christian, Foti, Michelangelo, Chanson, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977432/
https://www.ncbi.nlm.nih.gov/pubmed/36602863
http://dx.doi.org/10.1172/jci.insight.161961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977432/
https://www.ncbi.nlm.nih.gov/pubmed/36602863
http://dx.doi.org/10.1172/jci.insight.161961

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