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Acute high-fat diet impairs macrophage-supported intestinal damage resolution

Chronic exposure to high-fat diets (HFD) worsens intestinal disease pathology, but acute effects of HFD in tissue damage remain unclear. Here, we used short-term HFD feeding in a model of intestinal injury and found sustained damage with increased cecal dead neutrophil accumulation, along with dieta...

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Detalles Bibliográficos
Autores principales: Hill, Andrea A., Kim, Myunghoo, Zegarra-Ruiz, Daniel F., Chang, Lin-Chun, Norwood, Kendra, Assié, Adrien, Wu, Wan-Jung H., Renfroe, Michael C., Song, Hyo Wong, Major, Angela M., Samuel, Buck S., Hyser, Joseph M., Longman, Randy S., Diehl, Gretchen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977439/
https://www.ncbi.nlm.nih.gov/pubmed/36538527
http://dx.doi.org/10.1172/jci.insight.164489