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Target-mediated self-assembly of DNA networks for sensitive detection and intracellular imaging of APE1 in living cells

Herein, giant DNA networks were assembled from two kinds of functionalized tetrahedral DNA nanostructures (f-TDNs) for sensitive detection and intracellular imaging of apurinic/apyrimidinic endonuclease 1 (APE1) as well as gene therapy in tumor cells. Impressively, the reaction rate of the catalytic...

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Detalles Bibliográficos
Autores principales: Zhou, Xue-Mei, Zhuo, Ying, Yuan, Ruo, Chai, Ya-Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977452/
https://www.ncbi.nlm.nih.gov/pubmed/36873854
http://dx.doi.org/10.1039/d2sc06968g