Effect of mechanical unloading on genome-wide DNA methylation profile of the failing human heart

Heart failure (HF) is characterized by global alterations in myocardial DNA methylation, yet little is known about the epigenetic regulation of the noncoding genome and potential reversibility of DNA methylation with left ventricular assist device (LVAD) therapy. Genome-wide mapping of myocardial DN...

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Detalles Bibliográficos
Autores principales: Liao, Xianghai, Kennel, Peter J., Liu, Bohao, Nash, Trevor R., Zhuang, Richard Z., Godier-Furnemont, Amandine F., Xue, Chenyi, Lu, Rong, Colombo, Paolo C., Uriel, Nir, Reilly, Muredach P., Marx, Steven O., Vunjak-Novakovic, Gordana, Topkara, Veli K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977498/
https://www.ncbi.nlm.nih.gov/pubmed/36656640
http://dx.doi.org/10.1172/jci.insight.161788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977498/
https://www.ncbi.nlm.nih.gov/pubmed/36656640
http://dx.doi.org/10.1172/jci.insight.161788

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