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microRNA-33 deficiency in macrophages enhances autophagy, improves mitochondrial homeostasis, and protects against lung fibrosis

Idiopathic pulmonary fibrosis (IPF) is a progressive and ultimately fatal disease. Recent findings have shown a marked metabolic reprogramming associated with changes in mitochondrial homeostasis and autophagy during pulmonary fibrosis. The microRNA-33 (miR-33) family of microRNAs (miRNAs) encoded w...

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Detalles Bibliográficos
Autores principales: Ahangari, Farida, Price, Nathan L., Malik, Shipra, Chioccioli, Maurizio, Bärnthaler, Thomas, Adams, Taylor S., Kim, Jooyoung, Pradeep, Sai Pallavi, Ding, Shuizi, Cosmos, Carlos, Rose, Kadi-Ann S., McDonough, John E., Aurelien, Nachelle R., Ibarra, Gabriel, Omote, Norihito, Schupp, Jonas C., DeIuliis, Giuseppe, Villalba Nunez, Julian A., Sharma, Lokesh, Ryu, Changwan, Dela Cruz, Charles S., Liu, Xinran, Prasse, Antje, Rosas, Ivan, Bahal, Raman, Fernández-Hernando, Carlos, Kaminski, Naftali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977502/
https://www.ncbi.nlm.nih.gov/pubmed/36626225
http://dx.doi.org/10.1172/jci.insight.158100