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Pharmacological Activation of Rev-erbα Attenuates Doxorubicin-Induced Cardiotoxicity by PGC-1α Signaling Pathway

BACKGROUND: Doxorubicin-induced cardiotoxicity has been closely concerned in clinical practice. Rev-erbα is a transcriptional repressor that emerges as a drug target for heart diseases recently. This study is aimed at investigating the role and mechanism of Rev-erbα in doxorubicin-induced cardiotoxi...

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Detalles Bibliográficos
Autores principales: Zou, Runmei, Wang, Shuo, Cai, Hong, Wang, Yuwen, Wang, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977526/
https://www.ncbi.nlm.nih.gov/pubmed/36874248
http://dx.doi.org/10.1155/2023/2108584